Manuela Aragno Selected Research

Sympatholytics

2/2016	Dose-dependency of clonidine's effects in ascitic cirrhotic rats: comparison with α1-adrenergic agonist midodrine.
1/2016	Pathogenesis of solute-free water retention in experimental ascitic cirrhosis: is vasopressin the only culprit?
1/2016	Alpha-2A Adrenoceptor Agonist Guanfacine Restores Diuretic Efficiency in Experimental Cirrhotic Ascites: Comparison with Clonidine.

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Manuela Aragno Research Topics

Disease

14	Inflammation (Inflammations) 01/2022 - 02/2007
10	Ischemia 01/2020 - 09/2003
8	Neoplasms (Cancer) 01/2022 - 08/2003
8	Insulin Resistance 01/2021 - 10/2009
7	Reperfusion Injury 01/2020 - 01/2006
7	Fibrosis (Cirrhosis) 01/2020 - 11/2005
6	Liver Cirrhosis (Hepatic Cirrhosis) 01/2021 - 11/2005
5	Infarction (Infarctions) 01/2020 - 09/2008
5	Hyperglycemia 01/2012 - 12/2006
4	Non-alcoholic Fatty Liver Disease 01/2021 - 10/2009
4	Metabolic Diseases (Metabolic Disease) 01/2018 - 01/2013
3	Myocardial Ischemia (Ischemic Heart Diseases) 04/2020 - 01/2016
3	Type 2 Diabetes Mellitus (MODY) 01/2020 - 11/2007
3	Obesity 01/2020 - 01/2013
3	Body Weight (Weight, Body) 01/2018 - 02/2017
3	Ascites 01/2016 - 02/2008
3	Alzheimer Disease (Alzheimer's Disease) 10/2011 - 02/2008
3	Stroke (Strokes) 02/2009 - 01/2006
3	Hepatocellular Carcinoma (Hepatoma) 02/2008 - 08/2003
3	Cachexia 12/2007 - 08/2003
2	Diabetic Cardiomyopathies 04/2020 - 12/2006
2	Diabetes Mellitus 01/2020 - 01/2012
2	Portal Hypertension 01/2020 - 11/2005
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2018 - 10/2011
2	Hypoxia (Hypoxemia) 01/2016 - 02/2009
2	Atrophy 01/2015 - 07/2007
2	Lung Neoplasms (Lung Cancer) 07/2012 - 12/2007
2	Neuroblastoma 01/2012 - 10/2011
2	Necrosis 08/2010 - 12/2003
2	Brain Ischemia (Cerebral Ischemia) 01/2009 - 01/2006
2	Transient Ischemic Attack 09/2008 - 08/2006
1	Sepsis (Septicemia) 01/2022
1	Cytokine Release Syndrome 01/2022
1	Atherosclerosis 01/2022
1	Hodgkin Disease (Hodgkin's Disease) 01/2022
1	Asthma (Bronchial Asthma) 01/2022
1	Endometriosis 01/2022
1	COVID-19 01/2021

Drug/Important Bio-Agent (IBA)

11	FructoseIBA 01/2021 - 10/2009
8	Advanced Glycation End ProductsIBA 01/2022 - 11/2007
8	LipidsIBA 01/2019 - 12/2007
7	InflammasomesIBA 01/2022 - 01/2013
7	Dehydroepiandrosterone (DHEA)IBA 01/2021 - 09/2003
7	AntioxidantsIBA 01/2021 - 08/2006
6	SugarsIBA 01/2020 - 01/2013
5	CytokinesIBA 01/2022 - 08/2003
5	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 01/2012
5	Insulin (Novolin)FDA Link 01/2020 - 01/2009
5	Proteins (Proteins, Gene)FDA Link 01/2019 - 08/2003
4	EnzymesIBA 01/2022 - 02/2008
4	CholesterolIBA 01/2020 - 08/2010
4	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2013 - 08/2010
4	Streptozocin (Streptozotocin)FDA Link 01/2012 - 07/2007
4	Reactive Oxygen Species (Oxygen Radicals)IBA 02/2009 - 09/2002
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2008 - 08/2003
3	DiureticsIBA 02/2016 - 01/2016
3	Furosemide (Lasix)FDA LinkGeneric 02/2016 - 01/2016
3	SympatholyticsIBA 02/2016 - 01/2016
3	Carbon Tetrachloride (Tetrachloromethane)IBA 01/2016 - 02/2007
3	Interleukin-6 (Interleukin 6)IBA 07/2012 - 08/2003
3	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 10/2011 - 02/2008
3	Staphylococcal Protein A (Protein A)IBA 01/2009 - 08/2006
3	NF-kappa B (NF-kB)IBA 12/2006 - 09/2002
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2022 - 09/2008
2	Phosphotransferases (Kinase)IBA 01/2020 - 01/2016
2	Chymases (Chymase)IBA 01/2020 - 01/2016
2	Calcium-Sensing ReceptorsIBA 01/2020 - 07/2013
2	High Fructose Corn SyrupIBA 02/2017 - 01/2013
2	NucleotidesIBA 03/2016 - 01/2016
2	NLR ProteinsIBA 03/2016 - 01/2016
2	Clonidine (ST 155)FDA LinkGeneric 02/2016 - 01/2016
2	Adrenergic Agents (Adrenergic Drugs)IBA 01/2016 - 01/2016
2	Guanfacine (Tenex)FDA LinkGeneric 01/2016 - 01/2016
2	ProdrugsIBA 01/2016 - 01/2016
2	Amyloid (Amyloid Fibrils)IBA 01/2012 - 02/2009
2	pentosidineIBA 01/2012 - 11/2007
2	PPAR-gamma AgonistsIBA 08/2010 - 01/2006
2	PPAR gammaIBA 08/2010 - 01/2006
2	Pioglitazone (Actos)FDA Link 08/2010 - 01/2006
2	Amyloid beta-PeptidesIBA 02/2009 - 02/2008
2	4- benzyl- 2- methyl- 1,2,4- thiadiazolidine- 3,5- dioneIBA 01/2009 - 09/2008
2	Glycogen Synthase (Synthase I)IBA 01/2009 - 09/2008
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 09/2008 - 01/2006
2	Transcription Factors (Transcription Factor)IBA 12/2006 - 09/2002
1	Focal Adhesion Kinase 2IBA 01/2022
1	Interleukin-10 (Interleukin 10)IBA 01/2022
1	p38 Mitogen-Activated Protein KinasesIBA 01/2022
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2022
1	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 01/2022
1	E-SelectinIBA 01/2022
1	Peroxidase (Myeloperoxidase)IBA 01/2022
1	PF-562271IBA 01/2022
1	Focal Adhesion Protein-Tyrosine KinasesIBA 01/2022
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2021
1	CeramidesIBA 01/2021

Therapy/Procedure

4	Therapeutics 01/2022 - 11/2006
2	Radiotherapy 01/2020 - 11/2006
2	Drug Therapy (Chemotherapy) 07/2012 - 11/2006
1	Ligation 01/2022
1	Punctures 01/2022